Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 14/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.69 |
| ▸ | PIM1 | P11309 | 2/20 | 0.69 |
| ▸ | CCND1 | P24385 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26447945 | 1.00 | DYRK2 (1.00) | DYRK2CDK6PIM1CCND1 | |
| SCHEMBL30679275 | 0.90 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL26447920 | 0.90 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL26447927 | 0.90 | DYRK2 (1.00) | DYRK2CDK6PIM1 | |
| Hydrochloric Acid SCHEMBL26680013 | 0.90 | DYRK2 (0.99) | DYRK2CDK6PIM1 | |
| SCHEMBL26447926 | 0.89 | DYRK2 (1.00) | DYRK2 | |
| SCHEMBL30569709 | 0.89 | DYRK2 (1.00) | DYRK2 | |
| SCHEMBL31697604 | 0.88 | DYRK2 (1.00) | DYRK2CDK6PIM1CCND1 | |
| SCHEMBL31672936 | 0.86 | DYRK2 (0.83) | DYRK2CDK6PIM1CCND1 | |
| SCHEMBL26447966 | 0.86 | DYRK2 (0.83) | DYRK2CDK6PIM1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559485-B2 | CDK6/DYRK2 dual-target inhibitor, and preparation method therefor and use thereof | JIANGSU TASLY DIYI PHARMACEUTICAL CO. , LTD. (CN) | 2026-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559485-B2 | CDK6/DYRK2 dual-target inhibitor, and preparation method therefor and use thereof | CDK6, CDK2, CDKL1 | DYRK2 23/4885CDK6 1/4885PIM1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.