Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26964638 | 1.00 | UCHL1 (0.45) | UCHL1NR1H3CASP3GRM5SCN2A | |
| SCHEMBL30645657 | 0.79 | NR1H3 (0.51) | NR1H3CASP3GRM5MEN1APAF1 | |
| SCHEMBL26964772 | 0.79 | NR1H3 (0.51) | NR1H3CASP3GRM5MEN1APAF1 | |
| SCHEMBL30645633 | 0.76 | NR1H3 (0.48) | NR1H3CASP3GRM5MEN1APAF1 | |
| SCHEMBL26964577 | 0.76 | NR1H3 (0.48) | NR1H3CASP3GRM5MEN1APAF1 | |
| SCHEMBL25255372 | 0.76 | UCHL1 (0.44) | UCHL1 | |
| SCHEMBL17501098 | 0.72 | UCHL1 (0.58) | UCHL1MEN1KMT2A | |
| SCHEMBL26964761 | 0.67 | GRM5 (0.40) | NR1H3CASP3GRM5 | |
| SCHEMBL28711094 | 0.67 | UCHL1 (0.55) | UCHL1MEN1GAAKMT2A | |
| SCHEMBL17796390 | 0.67 | GRM5 (0.48) | NR1H3CASP3GRM5SCN2ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291176-A1 | CDK INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |