Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461208 | 1.00 | MAPT (0.52) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL2223232 | 0.78 | MAPT (0.66) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL5386301 | 0.76 | CA1 (0.76) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL29658293 | 0.76 | CA1 (0.76) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL28623792 | 0.73 | CA1 (0.50) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL8072508 | 0.73 | MAPT (0.74) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL10654200 | 0.72 | POLB (0.58) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL3248340 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL8469484 | 0.71 | ALDH1A1 (0.52) | ALDH1A1LMNACASP6CYP1A2 | |
| SCHEMBL6947889 | 0.70 | MAPT (0.54) | MAPTALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |