Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659537 | 0.82 | MAOA (0.48) | MAOAMAOBLMNAKMT2AMEN1 | |
| SCHEMBL14840333 | 0.79 | MAOA (0.43) | MAOAMAOBGSK3BLMNAKMT2A | |
| SCHEMBL1547476 | 0.79 | TDP1 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL10041694 | 0.79 | TRIM24 (0.42) | IDO1GSK3BNFATC1DYRK1ALMNA | |
| SCHEMBL31301252 | 0.77 | GSK3B (0.59) | IDO1MAOAMAOBGSK3BNFATC1 | |
| SCHEMBL31319806 | 0.76 | MAOA (0.43) | IDO1MAOAMAOBLMNAKMT2A | |
| SCHEMBL9042557 | 0.76 | MAOA (0.43) | IDO1MAOAMAOBLMNAKMT2A | |
| SCHEMBL2560775 | 0.76 | EIF4E (0.42) | MAOAMAOBLMNAKMT2AMEN1 | |
| SCHEMBL117895 | 0.75 | — | — | |
| SCHEMBL29954572 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |