Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 9/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534007 | 1.00 | PTGDR2 (0.49) | PTGDR2PTPN1PTGER1NPC1ALDH1A1 | |
| SCHEMBL13581057 | 0.88 | TUBB1 (0.51) | MAPTSLC6A4PPARGMAOAMAOB | |
| SCHEMBL25809975 | 0.86 | USP28 (0.61) | PTGDR2PTPN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2536145 | 0.86 | PPARD (0.45) | PTPN1ALDH1A1MAPTSLC6A4 | |
| SCHEMBL13764944 | 0.85 | SLC6A4 (0.43) | ALDH1A1LMNAMAPTSLC6A4PPARG | |
| SCHEMBL17294040 | 0.85 | SLC6A4 (0.57) | PTPN1MAPTCCR5SLC6A4 | |
| SCHEMBL5699854 | 0.84 | PTPN1 (0.64) | PTGDR2PTPN1PTGER1NPC1ALDH1A1 | |
| SCHEMBL30679655 | 0.84 | PTPN1 (0.64) | PTGDR2PTPN1PTGER1NPC1ALDH1A1 | |
| SCHEMBL2534809 | 0.83 | PTGER1 (0.49) | PTPN1PTGER1NPC1ALDH1A1LMNA | |
| SCHEMBL2534806 | 0.83 | PTGER1 (0.49) | PTPN1PTGER1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |