SCHEMBL30679657

SCHEMBL30679657

O=Cc1c(-c2cccc(Cl)c2)ccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.50
CYP1B1 Q16678 6/20 0.50
ERN1 O75460 3/20 0.46
CYP1A1 P04798 5/20 0.46
MIF P14174 1/20 0.41
MAPT P10636 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
FADS1 O60427 1/20 0.39
GLO1 Q04760 1/20 0.39
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3071898 0.82 ERN1 (0.56) CYP1A2CYP1B1ERN1CYP1A1MAPT
SCHEMBL14643530 0.80 ERN1 (0.47) CYP1A2CYP1B1ERN1MAPTCYP2C9
SCHEMBL19960402 0.79 ERN1 (0.46) CYP1A2CYP1B1ERN1CYP1A1MAPT
SCHEMBL14643663 0.79 ERN1 (0.46) CYP1A2CYP1B1ERN1CYP1A1MAPT
SCHEMBL380045 0.79 ERN1 (0.46) CYP1A2CYP1B1ERN1MAPTCYP2C9
SCHEMBL30679642 0.78 CYP1A1 (0.49) CYP1A2CYP1B1ERN1CYP1A1MAPT
SCHEMBL30679630 0.78 CYP1A1 (0.49) CYP1A2CYP1B1ERN1CYP1A1MAPT
SCHEMBL29391032 0.78 ERN1 (0.64) CYP1A2CYP1B1ERN1MAPTCYP2C9
SCHEMBL808500 0.78 ERN1 (0.64) CYP1A2CYP1B1ERN1MAPTCYP2C9
SCHEMBL380028 0.78 ERN1 (0.45) CYP1A2CYP1B1ERN1CYP1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430570-A Rhodamine acetic acid compound, and pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-01-23 CN disclosed