Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391032 | 1.00 | ERN1 (0.64) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3071898 | 0.88 | ERN1 (0.56) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23234176 | 0.87 | ERN1 (0.51) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL249731 | 0.87 | ERN1 (0.71) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9153615 | 0.84 | ERN1 (0.67) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5002573 | 0.84 | ERN1 (0.62) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21223045 | 0.83 | ERN1 (0.47) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14643530 | 0.83 | ERN1 (0.47) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9856898 | 0.83 | ERN1 (0.47) | ERN1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10898053 | 0.82 | ERN1 (0.50) | ERN1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457482-B9 | Stable isotope-labeled amino acid, method of integrating the same into target protein, method of NMR structural analysis of protein | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-10-24 | — | — | EP | disclosed |
| EP-1457482-B1 | Stable isotope-labeled amino acid, method of integrating the same into target protein, method of NMR structural analysis of protein | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-7022310-B2 | Stable isotope-labeled amino acid and method for incorporating same into target protein | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20050084452-A1 | Stable isotope-labeled amino acid and method for incorporating same into target protein | JAPANESE SCIENCE AND TECHNOLOGY AGENCY | 2005-04-21 | — | — | US | disclosed |
| EP-1457482-A1 | STABLE ISOTOPE-LABELED AMINO ACID, METHOD OF INTEGRATING THE SAME INTO TARGET PROTEIN, METHOD OF NMR STRUCTURAL ANALYSIS OF PROTEIN AND PROCESS FOR PRODUCING SITE-SELECTIVE STABLE ISOTOPE-LABELED FUMARIC ACID AND TARTARIC ACID | Japan Science and Technology Agency (JP) | 2004-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050084452-A1 | Stable isotope-labeled amino acid and method for incorporating same into target protein | GEMIN5, ATIC, AIP | ERN1 3870/4885MAPT 3325/4885CYP1A2 4429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.