Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948305 | 1.00 | HDAC1 (0.48) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL30679781 | 1.00 | HDAC1 (0.48) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL7407052 | 0.87 | HDAC1 (0.48) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL7239692 | 0.86 | CA2 (0.49) | HDAC1NAMPTCA1CA2 | |
| SCHEMBL31431173 | 0.84 | HDAC1 (0.47) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL31431581 | 0.84 | HDAC1 (0.48) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL21431046 | 0.84 | CA1 (0.42) | HDAC1L3MBTL1GRM2CA1CA2 | |
| SCHEMBL31738223 | 0.83 | GRM2 (0.49) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL31432277 | 0.83 | HDAC1 (0.46) | HDAC1L3MBTL1GRM2NAMPTCA1 | |
| SCHEMBL31432393 | 0.83 | CA1 (0.46) | HDAC1L3MBTL1GRM2NAMPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230407293-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | MAIANTI JUAN PABLO (US) | 2023-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230407293-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | DNA2, WRN, DCLRE1A | HDAC1 2718/4885L3MBTL1 1646/4885GRM2 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.