Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.54 |
| ▸ | FEN1 | P39748 | 17/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680156 | 0.83 | ALOX5AP (0.48) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL26585989 | 0.80 | ALOX5AP (0.50) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL24772742 | 0.79 | CYP3A4 (0.49) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL28981128 | 0.77 | ALOX5AP (0.54) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30718001 | 0.76 | ALOX5AP (0.52) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL24773007 | 0.76 | ALOX5AP (0.53) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL29126846 | 0.76 | ALOX5AP (0.58) | ALOX5APFEN1 | |
| SCHEMBL30680194 | 0.76 | ALOX5AP (0.58) | ALOX5APFEN1 | |
| SCHEMBL31128894 | 0.75 | EPHB4 (0.56) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31219436 | 0.74 | CYP3A4 (0.46) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222640-A | Heterocyclic compounds as FGFR inhibitors and uses thereof | 先声再明医药有限公司 | 2023-12-12 | — | — | CN | disclosed |