Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.50 |
| ▸ | FEN1 | P39748 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22676393 | 0.85 | ALOX5AP (0.46) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL24773521 | 0.82 | ALOX5AP (0.45) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30306048 | 0.82 | ALOX5AP (0.45) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL25714089 | 0.82 | ALOX5AP (0.45) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30680165 | 0.80 | ALOX5AP (0.54) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL24772742 | 0.80 | CYP3A4 (0.49) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL22677156 | 0.80 | ALOX5AP (0.43) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30717991 | 0.79 | ALOX5AP (0.50) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL17241848 | 0.78 | ALOX5AP (0.43) | ALOX5APFEN1MAPK14 | |
| SCHEMBL1643639 | 0.78 | GRM2 (0.42) | MAPK14TRPA1ROCK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |