Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716981 | 0.92 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL11722619 | 0.89 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL30996188 | 0.89 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL30680981 | 0.88 | ALDH1A1 (0.79) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL11718448 | 0.81 | KDM4E (0.53) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL30680916 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL11727213 | 0.78 | KDM4E (0.69) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL11717516 | 0.75 | KDM4E (0.53) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL14879442 | 0.74 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL11721556 | 0.73 | KDM4E (0.57) | ALDH1A1KMT2AKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244672-A1 | 2-(IMIDAZO[1, 2-A]1,8-NAPHTHYRIDIN-8-YL)-1,3,4-OXADIAZOLE DERIVATIVES AS ENHANCERS OF INNATE IMMUNE RESPONSE FOR THE TREATMENT OF VIRAL INFECTIONS | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-12-21 | — | — | WO | disclosed |