Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17382071 | 1.00 | MKNK1 (0.32) | MKNK1MKNK2NR1H4TGFBR1ACVR1 | |
| SCHEMBL30681681 | 0.91 | TGFBR1 (0.32) | NR1H4TGFBR1ACVR1 | |
| SCHEMBL17382057 | 0.91 | TGFBR1 (0.32) | NR1H4TGFBR1ACVR1 | |
| SCHEMBL16377702 | 0.91 | TGFBR1 (0.32) | NR1H4TGFBR1ACVR1 | |
| SCHEMBL17381648 | 0.90 | CCNA2 (0.35) | MKNK1MKNK2NR1H4ACVR1CCNA2 | |
| SCHEMBL16377961 | 0.89 | CYP11B1 (0.37) | MKNK1MKNK2NR1H4CYP11B1CYP11B2 | |
| SCHEMBL19321678 | 0.89 | NR1H4 (0.35) | MKNK1MKNK2NR1H4CCNA2CDK2 | |
| SCHEMBL30759604 | 0.88 | PDE7A (0.35) | MKNK1MKNK2TGFBR1ACVR1CCNA2 | |
| SCHEMBL27119255 | 0.88 | PDE7A (0.35) | MKNK1MKNK2TGFBR1ACVR1CCNA2 | |
| SCHEMBL17381651 | 0.88 | CCNA2 (0.32) | MKNK1MKNK2NR1H4CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157929-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | ARES TRADING SA (CH) | 2023-12-13 | — | — | EP | disclosed |