Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381645 | 1.00 | ROCK2 (0.39) | ROCK2ROCK1NR1H4 | |
| SCHEMBL16340073 | 0.88 | ROCK2 (0.37) | ROCK2ROCK1 | |
| SCHEMBL20988684 | 0.88 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL17381573 | 0.88 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL30886104 | 0.88 | NR1H4 (0.36) | NR1H4 | |
| SCHEMBL17381591 | 0.87 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL20731116 | 0.87 | CCNA2 (0.34) | ROCK2ROCK1NR1H4 | |
| SCHEMBL17381580 | 0.86 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL17382049 | 0.86 | NR1H4 (0.37) | NR1H4 | |
| SCHEMBL17381593 | 0.86 | NR1H4 (0.33) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157929-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | ARES TRADING SA (CH) | 2023-12-13 | — | — | EP | disclosed |