Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20731110 | 1.00 | NR1H4 (0.34) | NR1H4GPBAR1CCNA2CDK2CCNA1 | |
| SCHEMBL17381651 | 0.96 | CCNA2 (0.32) | NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL19321678 | 0.95 | NR1H4 (0.35) | NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL17381606 | 0.94 | NR1H4 (0.32) | NR1H4GPBAR1 | |
| SCHEMBL17382066 | 0.93 | CCNA2 (0.35) | NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL17382120 | 0.93 | ALPL (0.31) | CCNA2CDK2CCNA1 | |
| SCHEMBL17382238 | 0.92 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL17381637 | 0.92 | NR1H4 (0.35) | NR1H4GPBAR1CCNA2CDK2CCNA1 | |
| SCHEMBL17382067 | 0.92 | NR1H4 (0.33) | NR1H4GPBAR1 | |
| SCHEMBL17381970 | 0.91 | CCNA2 (0.32) | NR1H4CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157929-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | ARES TRADING SA (CH) | 2023-12-13 | — | — | EP | disclosed |