Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.43 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802309 | 0.88 | FOLH1 (0.53) | GNPATALDH1A1FOLH1NAALAD2RIMKLA | |
| SCHEMBL17305537 | 0.86 | ECE1 (0.43) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL29351596 | 0.85 | NOD1 (0.42) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL29351532 | 0.85 | NOD1 (0.42) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL156957 | 0.84 | GNPAT (0.44) | GNPATECE1KMT2ANOD1ALDH1A1 | |
| SCHEMBL156956 | 0.84 | GNPAT (0.44) | GNPATECE1KMT2ANOD1ALDH1A1 | |
| SCHEMBL15017971 | 0.84 | GNPAT (0.44) | GNPATECE1KMT2ANOD1ALDH1A1 | |
| SCHEMBL19177222 | 0.84 | GNPAT (0.44) | GNPATECE1KMT2ANOD1ALDH1A1 | |
| SCHEMBL29974699 | 0.84 | MAGI3 (0.53) | TASP1ALDH1A1MAGI3 | |
| SCHEMBL1764511 | 0.84 | GNPAT (0.54) | GNPATTASP1ECE1KMT2ANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116984-A1 | MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION | NATIONAL SCIENCE FOUNDATION | 2024-04-11 | — | — | US | disclosed |
| US-20230399361-A1 | MACROCYCLIC PEPTIDES | UNIVERSITY OF NOTRE DAME DU LAC | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116984-A1 | MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION | PRNP, MAPT, APP | GNPAT 4200/4885TASP1 590/4885ECE1 4106/4885 |
| US-20230399361-A1 | MACROCYCLIC PEPTIDES | APP, MAPT, NEFM | GNPAT 3748/4885TASP1 603/4885ECE1 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.