SCHEMBL30683243

SCHEMBL30683243

C=CC(=O)c1ccc2cc3ccccc3cc2c1C=O.[Al].[Cr]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 4/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 2/20 0.46
EGFR P00533 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
PKM P14618 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
JAK1 P23458 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GAA P10253 1/20 0.40
ERN1 O75460 3/20 0.37
AKT1 P31749 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564475 0.99 KDM4E (0.45) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL547795 0.80 WDR5 (0.47) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL3553966 0.77 KDM4E (0.61) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL2371288 0.72 ERN1 (0.70) ERN1
SCHEMBL547541 0.71 IDO1 (0.47) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL547570 0.70 IDO1 (0.46) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL548199 0.70 IDO1 (0.46) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL347177 0.70 ERN1 (0.43) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL4893713 0.69 ERN1 (0.50) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL545879 0.68 ERN1 (0.42) KDM4EALDH1A1MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11994296-B2 Combustion device having a flameless combustion chamber, use of such a device and electricity production or energy cogeneration apparatus comprising such a device MITIS S.A. (BE) 2024-05-28 US disclosed
US-20230392790-A1 COMBUSTION DEVICE HAVING A FLAMELESS COMBUSTION CHAMBER, USE OF SUCH A DEVICE AND ELECTRICITY PRODUCTION OR ENERGY COGENERATION APPARATUS COMPRISING SUCH A DEVICE UNIVERSITE LIBRE DE BRUXELLES (BE) 2023-12-07 US disclosed