Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26913227 | 1.00 | ROCK2 (0.33) | ROCK2MELKPIM1RPS6KB1ROCK1 | |
| SCHEMBL26913281 | 0.88 | CGAS (0.34) | RPS6KB1CGAS | |
| SCHEMBL30684398 | 0.84 | ROCK2 (0.36) | ROCK2MELKROCK1 | |
| SCHEMBL26912901 | 0.84 | ROCK2 (0.36) | ROCK2MELKROCK1 | |
| SCHEMBL26913077 | 0.84 | ROCK2 (0.36) | ROCK2MELKROCK1 | |
| SCHEMBL30684258 | 0.84 | ROCK2 (0.36) | ROCK2MELKROCK1 | |
| SCHEMBL26912886 | 0.82 | ROCK2 (0.35) | ROCK2MELKROCK1CGAS | |
| SCHEMBL30684417 | 0.82 | ROCK2 (0.35) | ROCK2MELKROCK1CGAS | |
| SCHEMBL30684362 | 0.81 | ROCK2 (0.34) | ROCK2MELKROCK1 | |
| SCHEMBL26912396 | 0.81 | ROCK2 (0.34) | ROCK2MELKROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |