Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CGAS | Q8N884 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26913846 | 1.00 | CGAS (0.33) | CGASROCK2JAK1 | |
| SCHEMBL30684348 | 0.91 | CGAS (0.33) | CGASROCK2JAK1 | |
| SCHEMBL30684406 | 0.91 | CGAS (0.33) | CGASROCK2JAK1 | |
| SCHEMBL26912604 | 0.91 | CGAS (0.33) | CGASROCK2JAK1 | |
| SCHEMBL26912994 | 0.91 | CGAS (0.33) | CGASROCK2JAK1 | |
| SCHEMBL30684417 | 0.90 | ROCK2 (0.35) | CGASROCK2 | |
| SCHEMBL26912886 | 0.90 | ROCK2 (0.35) | CGASROCK2 | |
| SCHEMBL26912229 | 0.87 | ROCK2 (0.33) | CGASROCK2 | |
| SCHEMBL30684392 | 0.84 | CGAS (0.33) | CGASROCK2 | |
| SCHEMBL26913059 | 0.84 | CGAS (0.33) | CGASROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |