Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082387 | 0.85 | POLB (0.57) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082354 | 0.84 | L3MBTL1 (0.54) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL30684803 | 0.83 | POLB (0.41) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082357 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082355 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082361 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082358 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082359 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082363 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL15082356 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CYP2C19MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110278711-B | Tricyclosulfones as rory modulators | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |