SCHEMBL30685103

SCHEMBL30685103

O=C(CNC12CC3CC(C1)CC(NCc1ccc(-c4ccccc4)cc1)(C3)C2)N1Cc2ccccc2C1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP9 Q86TI2 20/20 0.77
DPP8 Q6V1X1 19/20 0.77
GLMN Q92990 3/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685102 1.00 DPP9 (0.77) DPP9DPP8GLMN
SCHEMBL27357604 0.88 DPP9 (0.62) DPP9DPP8GLMN
SCHEMBL30685056 0.87 DPP9 (0.81) DPP9DPP8GLMN
SCHEMBL27355985 0.87 DPP9 (0.81) DPP9DPP8GLMN
SCHEMBL27356211 0.84 DPP9 (1.00) DPP9DPP8GLMN
Hydrochloric Acid SCHEMBL30685035 0.84 DPP9 (0.98) DPP9DPP8GLMN
SCHEMBL30685238 0.82 DPP9 (0.88) DPP9DPP8GLMN
SCHEMBL26240819 0.82 CNR2 (0.48) DPP9DPP8GLMN
SCHEMBL30685297 0.81 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL30685096 0.81 DPP9 (1.00) DPP9DPP8GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 WO disclosed