SCHEMBL30685155

SCHEMBL30685155

CC(C)(C)OC(=O)NC12C[C@@H]3C[C@@H](CC(N)(C3)C1)C2

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
DPP9 Q86TI2 7/20 0.50
DPP8 Q6V1X1 6/20 0.50
EPHX2 P34913 2/20 0.44
CACNA1H O95180 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
ITGB3 P05106 1/20 0.40
ITGA2B P08514 1/20 0.40
TSHR P16473 1/20 0.40
PBK Q96KB5 1/20 0.40
POLB P06746 1/20 0.39
ALOX15 P16050 1/20 0.38
PKM P14618 1/20 0.38
HSD11B1 P28845 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15191498 1.00 MEN1 (0.54) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL6229153 0.84 DPP8 (0.47) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL13287421 0.84 MEN1 (0.55) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL5802496 0.83 MEN1 (0.51) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL136224 0.82 KMT2A (0.73) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL25736662 0.82 MEN1 (0.54) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL2221231 0.81 MEN1 (0.52) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL16259930 0.81 MEN1 (0.52) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL20243118 0.81 MEN1 (0.41) MEN1MAPK1KMT2ADPP9DPP8
SCHEMBL5804382 0.80 MEN1 (0.51) MEN1MAPK1KMT2ADPP9DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353833-A1 DPP9 BINDING COMPOUNDS UNIV ANTWERPEN (BE) 2025-11-20 US disclosed
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353833-A1 DPP9 BINDING COMPOUNDS DPP9, DPP7, DPP3 MEN1 3346/4885MAPK1 2779/4885KMT2A 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.