Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | DNA2 | P51530 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520291 | 1.00 | POLB (0.40) | POLBTSHRLMNAMAPTHTT | |
| SCHEMBL30686029 | 0.85 | POLB (0.59) | POLBLMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL28908061 | 0.85 | POLB (0.59) | POLBLMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL28519693 | 0.84 | LMNA (0.46) | POLBTSHRLMNAMAPTHTT | |
| SCHEMBL30686011 | 0.84 | LMNA (0.46) | POLBTSHRLMNAMAPTHTT | |
| SCHEMBL28534508 | 0.81 | CYP1A2 (0.35) | POLBTSHRLMNAMAPTHTT | |
| SCHEMBL30686034 | 0.81 | CYP1A2 (0.35) | POLBTSHRLMNAMAPTHTT | |
| SCHEMBL30686019 | 0.79 | MEN1 (0.46) | POLBMAPTHTTKMT2AALDH1A1 | |
| SCHEMBL28519202 | 0.79 | MEN1 (0.46) | POLBMAPTHTTKMT2AALDH1A1 | |
| SCHEMBL10625918 | 0.79 | PIK3CG (0.51) | LMNAMAPTHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409332-B | Triazole derivative and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |