Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27028742 | 1.00 | GRIK1 (0.32) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL6674233 | 0.77 | FAAH (0.32) | — | |
| SCHEMBL29086756 | 0.73 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL7164140 | 0.72 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL466127 | 0.72 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL6673351 | 0.72 | GRIK1 (0.32) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL2973406 | 0.72 | GRIK1 (0.36) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL2973400 | 0.72 | GRIK1 (0.36) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL5764966 | 0.71 | SLC6A2 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL27395046 | 0.71 | GRIK1 (0.38) | GRIK1GRIK2CYP2C19CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |