Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 3/20 | 0.38 |
| ▸ | MDM4 | O15151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16288773 | 1.00 | FABP5 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL30744237 | 1.00 | FABP5 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL20604252 | 1.00 | FABP5 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL16288775 | 1.00 | FABP5 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL25179599 | 0.91 | CASP3 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL25179598 | 0.91 | CASP3 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL30802516 | 0.91 | CASP3 (0.38) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL16310687 | 0.88 | FABP5 (0.40) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL24633869 | 0.87 | FABP5 (0.43) | FABP5FABP7CASP3MDM4TP53 | |
| SCHEMBL30792912 | 0.87 | FABP5 (0.43) | FABP5FABP7CASP3MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202211-A | Cyclic compounds having selective KRAS inhibition over HRAS and NRAS | 中外制药株式会社 | 2025-06-24 | — | — | CN | disclosed |
| CN-119731195-A | Cyclic compounds having selective inhibition of KRAS over HRAS and NRAS | 中外制药株式会社 | 2025-03-28 | — | — | CN | disclosed |
| CN-117279655-A | Pharmaceutical use of cyclic peptide compounds | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |