Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | FABP7 | O15540 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050272 | 1.00 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL4038089 | 1.00 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL4448418 | 1.00 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL3423135 | 1.00 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL30686135 | 1.00 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL5256666 | 0.94 | FABP5 (0.44) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL16179303 | 0.89 | KMT2A (0.45) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL30363018 | 0.88 | FABP5 (0.45) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL4040012 | 0.88 | FABP5 (0.45) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL1675971 | 0.86 | FABP5 (0.50) | FABP5FABP7KMT2AEPHX2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |