Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.50 |
| ▸ | FABP7 | O15540 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675974 | 1.00 | FABP5 (0.50) | FABP5FABP7TACR1KMT2AEPHX2 | |
| SCHEMBL31582094 | 0.90 | FABP5 (0.43) | FABP5FABP7KMT2AEPHX2MDM4 | |
| SCHEMBL31524267 | 0.90 | FABP5 (0.43) | FABP5FABP7KMT2AEPHX2MDM4 | |
| SCHEMBL2906513 | 0.88 | FABP5 (0.42) | FABP5FABP7KMT2AEPHX2SLC6A4 | |
| SCHEMBL7202660 | 0.88 | FABP5 (0.52) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL1827945 | 0.88 | FABP5 (0.52) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL7202664 | 0.88 | FABP5 (0.52) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL30686169 | 0.86 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL30686135 | 0.86 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 | |
| SCHEMBL3423135 | 0.86 | FABP5 (0.47) | FABP5FABP7KMT2AEPHX2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092445-A1 | Amyloid ß peptide analogues, oligomers thereof, processes for preparing and composi-tions comprising said analogues or oligomers, and their uses | ABBOTT LABORATORIES (US) | 2011-04-21 | — | — | US | disclosed |
| EP-2303920-A2 | AMYLOID ß PEPTIDE ANALOGUES, OLIGOMERS THEREOF, PROCESSES FOR PREPARING AND COMPOSITIONS COMPRISING SAID ANALOGUES OR OLIGOMERS, AND THEIR USES | Abbott Laboratories (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010011947-A2 | AMYLOID ß PEPTIDE ANALOGUES, OLIGOMERS THEREOF, PROCESSES FOR PREPARING AND COMPOSITIONS COMPRISING SAID ANALOGUES OR OLIGOMERS, AND THEIR USES | ABBOTT LABORATORIES (US) | 2010-01-28 | — | — | WO | disclosed |
| US-5856439-A | ANTICANCER AGENT | RHONE-POULENC RORER S.A. (FR) | 1999-01-05 | — | — | US | disclosed |
| EP-0808328-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024611-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1996-08-15 | — | — | WO | disclosed |