Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.36 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18096347 | 0.89 | PRKCQ (0.46) | PRKCQHDAC1CSNK1EPRKAB2PRKAG1 | |
| SCHEMBL31368899 | 0.79 | LATS1 (0.39) | PRKCQPOLBTDP1HDAC1CSNK1E | |
| SCHEMBL17371708 | 0.78 | POLB (0.55) | POLBTDP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL18096093 | 0.78 | PRKCQ (0.53) | PRKCQHDAC1CSNK1EIRAK4AURKA | |
| SCHEMBL17075539 | 0.75 | PRKAB2 (0.58) | POLBTDP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL16339295 | 0.74 | HDAC1 (0.42) | PRKCQHDAC1CSNK1EIRAK4AURKB | |
| SCHEMBL19995495 | 0.74 | PRKCQ (0.44) | PRKCQHDAC1CSNK1EIRAK4AURKA | |
| SCHEMBL16333395 | 0.73 | POLB (0.40) | POLBTDP1HDAC1PRKAB2PRKAG1 | |
| SCHEMBL16378116 | 0.73 | POLB (0.49) | POLBTDP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL20000452 | 0.72 | PRKCQ (0.61) | PRKCQHDAC1CSNK1EIRAK4PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532496-A1 | NOVEL PAR-2 INHIBITORS | Domain Therapeutics (FR) | 2025-04-09 | — | — | EP | claimed |
| WO-2023233033-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2023-12-07 | — | — | WO | claimed |