Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175561 | 1.00 | ACHE (0.54) | ACHELMNAMKNK1MKNK2AR | |
| SCHEMBL35210101 | 0.87 | ACHE (0.57) | ACHE | |
| SCHEMBL659349 | 0.81 | ACHE (0.64) | ACHELMNAMKNK1MKNK2ADORA2A | |
| SCHEMBL29399366 | 0.80 | ACHE (0.54) | ACHELMNAMKNK1MKNK2AR | |
| SCHEMBL25819849 | 0.80 | ACHE (0.49) | ACHELMNAMKNK1MKNK2MAPKAPK2 | |
| SCHEMBL28309802 | 0.80 | ACHE (0.49) | ACHELMNAMKNK1MKNK2MAPKAPK2 | |
| SCHEMBL12862846 | 0.78 | ACHE (0.47) | ACHELMNAMKNK1MKNK2MAPKAPK2 | |
| SCHEMBL566139 | 0.78 | ACHE (0.50) | ACHELMNAMKNK1MKNK2 | |
| SCHEMBL30961721 | 0.75 | ACHE (0.51) | ACHELMNAMKNK1MKNK2 | |
| SCHEMBL22399206 | 0.75 | ACHE (0.68) | ACHELMNAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531856-B1 | BRUTON'S KINASE INHIBITORS FOR THE TREATMENT OF A SUDDEN ALLERGIC REACTION | ALK ABELLO AS (DK) | 2026-04-22 | — | — | EP | claimed |
| WO-2025083736-A1 | NOVEL PROCESS FOR THE PREPARATION OF PIRTOBRUTINIB AND ITS INTERMEDIATES THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2025-04-24 | — | — | WO | disclosed |
| EP-4531856-A1 | BRUTON'S KINASE INHIBITORS FOR THE TREATMENT OF A SUDDEN ALLERGIC REACTION | ALK-Abelló A/S (DK) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023232958-A1 | BRUTON'S KINASE INHIBITORS FOR THE TREATMENT OF A SUDDEN ALLERGIC REACTION | Alk-Abelló A/S (DK) | 2023-12-07 | — | — | WO | disclosed |