Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 14/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | TFPI | P10646 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018311 | 0.93 | BACE1 (0.53) | BACE1CTSDHRH1 | |
| SCHEMBL30686822 | 0.93 | BACE1 (0.55) | BACE1TFPICTSDBACE2HRH1 | |
| SCHEMBL30769684 | 0.92 | TFPI (0.57) | BACE1PTPN1TFPIBACE2HRH1 | |
| SCHEMBL31738162 | 0.90 | BACE1 (0.62) | BACE1TFPI | |
| SCHEMBL29777765 | 0.90 | BACE1 (0.59) | BACE1PTPN1CTSDBACE2 | |
| SCHEMBL31603949 | 0.89 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL29720238 | 0.89 | BACE1 (0.57) | BACE1TFPICTSD | |
| SCHEMBL29904367 | 0.89 | OPRK1 (0.56) | — | |
| SCHEMBL2520304 | 0.87 | NAALAD2 (0.56) | BACE1BACE2 | |
| SCHEMBL2520307 | 0.87 | NAALAD2 (0.56) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186201-A | Branched chain modified EGF (A) analogue and application thereof | 乐普（北京）医疗器械股份有限公司 | 2023-12-08 | — | — | CN | disclosed |