Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26681491 | 1.00 | CHRM3 (0.49) | CHRM3HTTALDH1A1POLBDRD3 | |
| SCHEMBL26681124 | 0.89 | CHRM3 (0.47) | CHRM3HTTALDH1A1POLBDRD3 | |
| SCHEMBL30687571 | 0.88 | DRD3 (0.44) | HTTDRD3CHRM4DRD2PPARD | |
| SCHEMBL26681006 | 0.88 | DRD3 (0.44) | HTTDRD3CHRM4DRD2PPARD | |
| SCHEMBL30687743 | 0.88 | CHRM3 (0.46) | CHRM3DRD3PRKD1CHRM4DRD2 | |
| SCHEMBL26682995 | 0.88 | CHRM3 (0.46) | CHRM3DRD3PRKD1CHRM4DRD2 | |
| SCHEMBL26682582 | 0.86 | BCL2 (0.49) | CHRM3ALDH1A1PPARDPPARAKDM4E | |
| SCHEMBL26681750 | 0.86 | PPARD (0.46) | CHRM3ALDH1A1DRD3DRD2PPARD | |
| SCHEMBL26682383 | 0.86 | CHRM3 (0.45) | CHRM3CHRM4TP53CHRM2 | |
| SCHEMBL26682336 | 0.85 | ALDH1A1 (0.47) | ALDH1A1POLBDRD3PRKD1CHRNA10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |