SCHEMBL30688063

SCHEMBL30688063

C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(=O)[C@@](C)(CO)[C@@H]5CC[C@]43C)[C@@H]12

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 9/20 0.80
▸ NT5E P21589 3/20 0.80
▸ LMNA P02545 2/20 0.80
▸ SMN1; SMN2 Q16637 1/20 0.80
▸ CES2 O00748 2/20 0.70
▸ CES1 P23141 2/20 0.70
▸ F3 P13726 1/20 0.70
▸ PTPN1 P18031 2/20 0.65
▸ GLI1 P08151 2/20 0.65
▸ USP2 O75604 1/20 0.65
▸ HIF1A Q16665 1/20 0.65
▸ AKR1B10 O60218 1/20 0.65
▸ ALB P02768 1/20 0.65
▸ POLB P06746 1/20 0.65
▸ AKR1B1 P15121 1/20 0.65
▸ DPP4 P27487 1/20 0.65
▸ RORC P51449 1/20 0.65
▸ SAE1 Q9UBE0 1/20 0.65
▸ UBA2 Q9UBT2 1/20 0.65
▸ RELA Q04206 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15450723 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL14554424 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL14023068 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL16704974 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL14134274 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL3507861 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL13184576 1.00 GPBAR1 (0.80) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL14134563 0.94 GPBAR1 (0.81) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL16704632 0.94 GPBAR1 (0.69) GPBAR1NT5ELMNASMN1; SMN2CES2
SCHEMBL15445087 0.94 GPBAR1 (0.69) GPBAR1NT5ELMNASMN1; SMN2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4529452-B1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI SPA (IT) 2025-12-24 — — EP claimed
US-20250170038-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI S.P.A. (IT) 2025-05-29 — — US claimed
EP-4529452-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES Giuliani S.p.A. (IT) 2025-04-02 — — EP claimed
WO-2023228079-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI S.P.A. (IT) 2023-11-30 — — WO claimed
EP-4529452-B1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI SPA (IT) 2025-12-24 — — EP disclosed
US-20250170038-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI S.P.A. (IT) 2025-05-29 — — US disclosed
EP-4529452-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES Giuliani S.p.A. (IT) 2025-04-02 — — EP disclosed
CN-119654128-A Dosage forms for topical administration of pentacyclic triterpenes 朱利亚尼股份公司 2025-03-18 — — CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
WO-2023228079-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI S.P.A. (IT) 2023-11-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170038-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES MAS1, CYP51A1, EYA2 GPBAR1 1876/4885NT5E 2951/4885LMNA 3628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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