Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22436411 | 1.00 | KDM4E (0.43) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28433225 | 0.91 | JAK3 (0.41) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29130407 | 0.83 | EGFR (0.38) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30688440 | 0.83 | EGFR (0.38) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29130409 | 0.83 | EGFR (0.38) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22436381 | 0.83 | KDM4E (0.46) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22436382 | 0.83 | KDM4E (0.46) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26447147 | 0.82 | MAPK1 (0.47) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22436438 | 0.81 | PSMB5 (0.43) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26096253 | 0.81 | PSMB5 (0.43) | KDM4EMAPK1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491939-B | Immunoproteasome inhibitors | 普林斯匹亚生物制药公司 | 2023-12-26 | — | — | CN | disclosed |