Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970789 | 1.00 | BRD4 (0.35) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL30689020 | 0.85 | RET (0.35) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL4651581 | 0.85 | RET (0.35) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL1703192 | 0.85 | RET (0.35) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL9142051 | 0.83 | RET (0.34) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL9142065 | 0.83 | RET (0.34) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL7061731 | 0.83 | RET (0.34) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL9148551 | 0.83 | RET (0.34) | BRD4CCL2RETSIGMAR1HTR2A | |
| Lithium SCHEMBL9148569 | 0.83 | RET (0.34) | BRD4CCL2RETSIGMAR1HTR2A | |
| SCHEMBL8964850 | 0.83 | RET (0.34) | BRD4CCL2RETSIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974105-A | Olefin polymerization catalyst comprising magnesium, titanium, epoxy compounds and internal electron donors such as compounds based on 1, 2-phenylene dibenzoate | 格雷斯公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-117355546-A | Spherical catalyst component for olefin polymerization | 格雷斯公司 | 2024-01-05 | — | — | CN | disclosed |