SCHEMBL1703192

SCHEMBL1703192

CO[Si](OC)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.35
HTR2A P28223 2/20 0.34
HTR6 P50406 1/20 0.34
SIGMAR1 Q99720 6/20 0.32
CYP2D6 P10635 2/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30689020 1.00 RET (0.35) RETHTR2AHTR6SIGMAR1CYP2D6
SCHEMBL1703375 0.87 GPR3 (0.31) RETHTR2ACYP2D6KDM4ELMNA
SCHEMBL28916605 0.85 CYP2D6 (0.32) CYP2D6
SCHEMBL30689015 0.85 BRD4 (0.35) RETHTR2AHTR6SIGMAR1CYP2D6
SCHEMBL4651581 0.85 RET (0.35) RETHTR2AHTR6SIGMAR1CYP2D6
SCHEMBL970789 0.85 BRD4 (0.35) RETHTR2AHTR6SIGMAR1CYP2D6
SCHEMBL8964850 0.83 RET (0.34) RETHTR2AHTR6SIGMAR1CYP2D6
SCHEMBL9142065 0.83 RET (0.34) RETHTR2AHTR6SIGMAR1CYP2D6
SCHEMBL9148551 0.83 RET (0.34) RETHTR2AHTR6SIGMAR1CYP2D6
Lithium SCHEMBL9148569 0.83 RET (0.34) RETHTR2AHTR6SIGMAR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428716-B Catalyst system, olefin polymerization catalyst component comprising at least an internal electron donor compound, and methods of making and using the same 格雷斯公司 2021-05-11 CN claimed
US-10689465-B2 External donor for olefin polymerization INDIAN OIL CORPORATION LIMITED (IN) 2020-06-23 US claimed
EP-3653631-A1 PROCESSES FOR THE PREPARATION OF AN OLEFIN POLYMERIZATION CATALYST BASED ON TREATING SOLID ORGANOMAGNESIUM COMPOUNDS WITH TITANIUM MOIETIES INDIAN OIL CORPORATION Ltd. (IN) 2020-05-20 EP claimed
US-10611865-B2 Organometallic compound in solid form, process for preparing the same and use thereof INDIAN OIL CORPORATION LIMITED (IN) 2020-04-07 US claimed
US-20180362675-A1 EXTERNAL DONOR FOR OLEFIN POLYMERIZATION INDIAN OIL CORPORATION LIMITED (IN) 2018-12-20 US claimed
EP-3415541-A1 EXTERNAL DONOR FOR OLEFIN POLYMERIZATION INDIAN OIL CORPORATION Ltd. (IN) 2018-12-19 EP claimed
US-20180355082-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2018-12-13 US claimed
US-20170081440-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2017-03-23 US claimed
US-20150274857-A1 DISTANCE MEASURING METHOD AND DISTANCE MEASURING ELEMENT INDIAN OIL CORPORATION LIMITED (IN) 2015-10-01 US claimed
EP-2897966-A2 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF Indian Oil Corporation Ltd (IN) 2015-07-29 EP claimed
EP-2897965-A2 PRECURSOR FOR CATALYST, PROCESS FOR PREPARING THE SAME AND ITS USE THEREOF Indian Oil Corporation Ltd (IN) 2015-07-29 EP claimed
US-20150191553-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2015-07-09 US claimed
WO-2014045260-A2 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2014-03-27 WO claimed
WO-2014045259-A2 PRECURSOR FOR CATALYST, PROCESS FOR PREPARING THE SAME AND ITS USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2014-03-27 WO claimed
EP-3676300-B1 OLEFIN POLYMERIZATION CATALYST GRACE W R & CO (US) 2026-05-13 EP disclosed
EP-3592783-B1 ELECTRON DONORS FOR ZIEGLER-NATTA PRECATALYST PREPARATION AND CATALYST SYSTEM FOR OLEFIN POLYMERIZATION GRACE W R & CO (US) 2025-11-12 EP disclosed
US-20250109220-A1 Olefin Polymerization Catalyst Comprising Magnesium, Titanium, an Epoxy Compound and an Internal Electron Donor, Such as a 1,2-Phenylene Dibenzoate-Based Compound W. R. GRACE & CO.-CONN. 2025-04-03 US disclosed
EP-0350170-B1 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL IND (JP) 1994-03-02 EP disclosed
US-4990479-A Coordination catalysts MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed
EP-0350170-A2 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180355082-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF MLX, BRIX1, CYP4X1 RET 2550/4885HTR2A 3732/4885HTR6 4067/4885
US-10611865-B2 Organometallic compound in solid form, process for preparing the same and use thereof MLX, BRIX1, CYP4X1 RET 2550/4885HTR2A 3732/4885HTR6 4067/4885
US-20150274857-A1 DISTANCE MEASURING METHOD AND DISTANCE MEASURING ELEMENT MLX, PRDX2, NFXL1 RET 3840/4885HTR2A 3715/4885HTR6 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.