Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801756 | 0.86 | TSHR (0.55) | MAPTTSHRGSTP1SMN1; SMN2SIRT2 | |
| SCHEMBL30689348 | 0.85 | IP6K1 (0.41) | TSHRGSTP1 | |
| SCHEMBL27291368 | 0.80 | ACACB (0.39) | MAPTGSTP1SMN1; SMN2 | |
| SCHEMBL23588077 | 0.80 | ACACB (0.52) | MAPTFFAR1SMN1; SMN2 | |
| SCHEMBL25802137 | 0.79 | MAPT (0.50) | MAPTTSHRFFAR1SMN1; SMN2MAPK1 | |
| SCHEMBL30006188 | 0.78 | LTA4H (0.46) | FPR2SCN9AMAPTTSHRFFAR1 | |
| SCHEMBL27204735 | 0.78 | LTA4H (0.42) | FPR2SCN9AMAPTTSHRFFAR1 | |
| SCHEMBL24664144 | 0.78 | LTA4H (0.46) | FPR2SCN9AMAPTTSHRFFAR1 | |
| SCHEMBL27171401 | 0.78 | LTA4H (0.42) | FPR2SCN9AMAPTTSHRFFAR1 | |
| SCHEMBL25802130 | 0.78 | TP53 (0.42) | MAPTTSHRSMN1; SMN2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |