Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689324 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2PDE10ASSTR4KDM4E | |
| SCHEMBL1589578 | 0.85 | SSTR4 (0.42) | HCRTR1HCRTR2KCNMA1SSTR4ALDH1A1 | |
| SCHEMBL12702468 | 0.85 | SSTR4 (0.42) | HCRTR1HCRTR2KCNMA1SSTR4ALDH1A1 | |
| SCHEMBL1589577 | 0.85 | SSTR4 (0.42) | HCRTR1HCRTR2KCNMA1SSTR4ALDH1A1 | |
| SCHEMBL30689381 | 0.85 | HCRTR1 (0.47) | HCRTR1HCRTR2PDE10ASSTR4ALDH1A1 | |
| SCHEMBL21855559 | 0.81 | HCRTR1 (0.44) | HCRTR1HCRTR2PDE10ASSTR4SSTR1 | |
| SCHEMBL21855561 | 0.81 | HCRTR1 (0.44) | HCRTR1HCRTR2PDE10ASSTR4SSTR1 | |
| SCHEMBL29134131 | 0.80 | KDM4E (0.49) | HCRTR1HCRTR2SSTR4ALDH1A1SSTR1 | |
| SCHEMBL15696551 | 0.80 | HCRTR1 (0.46) | HCRTR1HCRTR2PDE10AAXLTYRO3 | |
| SCHEMBL15800230 | 0.80 | HCRTR1 (0.46) | HCRTR1HCRTR2PDE10AAXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |