Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 6/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689425 | 0.89 | MAPT (0.42) | PPARGTP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL30689359 | 0.86 | IP6K1 (0.39) | PPARGTP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL30689377 | 0.85 | GSTP1 (0.38) | PPARGTP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL30689426 | 0.85 | CNR2 (0.41) | PPARGMAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL30689373 | 0.83 | PPARG (0.39) | PPARGTP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL31527931 | 0.76 | MAPT (0.42) | PPARGTP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL30689307 | 0.75 | LTA4H (0.52) | TP53MAPTLMNALTA4HKCNH2 | |
| SCHEMBL30689409 | 0.73 | FFAR4 (0.41) | TP53ALDH1A1KMT2AGSTP1FFAR1 | |
| SCHEMBL31527827 | 0.72 | TP53 (0.46) | TP53MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31527938 | 0.72 | GSTP1 (0.39) | TP53MAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |