Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689293 | 0.89 | DRD1 (0.38) | GSTP1DRD1 | |
| SCHEMBL30689425 | 0.79 | MAPT (0.42) | PPARGTP53MAPTDRD1TSHR | |
| SCHEMBL31527877 | 0.77 | GSTP1 (0.44) | PPARGGSTP1TP53DRD1 | |
| SCHEMBL30689426 | 0.77 | CNR2 (0.41) | PPARGGSTP1MAPT | |
| SCHEMBL30689373 | 0.75 | PPARG (0.39) | PPARGTP53FFAR4MAPTDRD1 | |
| SCHEMBL30689352 | 0.72 | PPARG (0.38) | PPARGGSTP1TP53MAPT | |
| SCHEMBL31527956 | 0.71 | GSTP1 (0.43) | PPARGGSTP1TP53MAPTTSHR | |
| SCHEMBL31527931 | 0.71 | MAPT (0.42) | PPARGGSTP1TP53MAPTTSHR | |
| SCHEMBL30689460 | 0.70 | GSTP1 (0.49) | PPARGGSTP1TP53MAPTTSHR | |
| SCHEMBL30689444 | 0.70 | SCN7A (0.38) | PPARGGSTP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968366-A | Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases | 西特瑞治疗有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119968366-A | Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases | 西特瑞治疗有限公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |