Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.44 |
| ▸ | CTSK | P43235 | 8/20 | 0.43 |
| ▸ | ATM | Q13315 | 9/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541777 | 1.00 | CTSS (0.44) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541731 | 0.89 | CTSS (0.42) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541816 | 0.88 | CTSS (0.42) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541869 | 0.88 | CTSS (0.44) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541789 | 0.87 | ATM (0.48) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541751 | 0.81 | PRKDC (0.59) | CTSSCTSKATMPRKDC | |
| SCHEMBL29559426 | 0.81 | PRKDC (0.59) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541788 | 0.80 | ATM (0.45) | CTSSCTSKATMPRKDC | |
| SCHEMBL21541808 | 0.79 | S1PR1 (0.37) | — | |
| SCHEMBL21541838 | 0.78 | ATM (0.39) | CTSSATMPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |