Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.41 |
| ▸ | WNT1 | P04628 | 13/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690744 | 0.96 | DYRK1A (0.43) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690447 | 0.96 | DYRK1A (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690738 | 0.92 | GSK3B (0.49) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690451 | 0.92 | GSK3B (0.39) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690525 | 0.91 | GSK3B (0.42) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690587 | 0.91 | GSK3B (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690654 | 0.91 | GSK3B (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL27273394 | 0.91 | GSK3B (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690585 | 0.91 | GSK3B (0.40) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690436 | 0.91 | GSK3B (0.41) | GSK3BDYRK1AWNT1KITCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |