Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 12/20 | 0.43 |
| ▸ | GSK3B | P49841 | 11/20 | 0.43 |
| ▸ | WNT1 | P04628 | 10/20 | 0.43 |
| ▸ | KIT | P10721 | 5/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690447 | 0.97 | DYRK1A (0.46) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690486 | 0.96 | GSK3B (0.41) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690436 | 0.94 | GSK3B (0.41) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690738 | 0.93 | GSK3B (0.49) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690525 | 0.93 | GSK3B (0.42) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690585 | 0.92 | GSK3B (0.40) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690723 | 0.92 | KIT (0.43) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690655 | 0.92 | GSK3B (0.41) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690538 | 0.90 | GSK3B (0.44) | DYRK1AGSK3BWNT1KITCSF1R | |
| SCHEMBL30690654 | 0.90 | GSK3B (0.46) | DYRK1AGSK3BWNT1KITCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |