Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 12/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690532 | 0.88 | GSK3B (0.47) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690579 | 0.88 | WNT1 (0.37) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690718 | 0.84 | MLLT1 (0.40) | WNT1GSK3BDYRK1AKIT | |
| SCHEMBL30690525 | 0.83 | GSK3B (0.42) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690722 | 0.82 | MAPT (0.40) | WNT1GSK3BDYRK1AKIT | |
| SCHEMBL30690514 | 0.80 | GSK3B (0.46) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690592 | 0.80 | KIT (0.41) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690738 | 0.79 | GSK3B (0.49) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690447 | 0.79 | DYRK1A (0.46) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690587 | 0.78 | GSK3B (0.46) | WNT1GSK3BDYRK1AKITCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |