Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | WNT1 | P04628 | 3/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MLLT3 | P42568 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690504 | 0.90 | HRH3 (0.39) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690482 | 0.86 | KIT (0.41) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690653 | 0.83 | KIT (0.44) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL27275910 | 0.82 | KIT (0.41) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690737 | 0.82 | KIT (0.41) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690581 | 0.82 | HRH3 (0.37) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690762 | 0.82 | GSK3B (0.38) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690710 | 0.82 | KIT (0.49) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690609 | 0.81 | GSK3B (0.49) | HRH3SMN1; SMN2RECQLKITGSK3B | |
| SCHEMBL30690516 | 0.81 | GSK3B (0.37) | HRH3SMN1; SMN2RECQLKITGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |