Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690504 | 0.93 | HRH3 (0.39) | KITHRH3SMN1; SMN2RECQLWNT1 | |
| SCHEMBL30690767 | 0.88 | KIT (0.45) | KITULK1BTKSMN1; SMN2MEN1 | |
| SCHEMBL30690653 | 0.88 | KIT (0.44) | KITHRH3BTKSMN1; SMN2RECQL | |
| SCHEMBL30690442 | 0.86 | KIT (0.41) | KITULK1BTK | |
| SCHEMBL27275910 | 0.86 | KIT (0.41) | KITHRH3SMN1; SMN2RECQLWNT1 | |
| SCHEMBL30690737 | 0.86 | KIT (0.41) | KITHRH3SMN1; SMN2RECQLWNT1 | |
| SCHEMBL30690692 | 0.86 | HRH3 (0.36) | KITHRH3SMN1; SMN2RECQLWNT1 | |
| SCHEMBL30690443 | 0.85 | CCNE1 (0.40) | HRH3SMN1; SMN2RECQLWNT1GSK3B | |
| SCHEMBL30690710 | 0.85 | KIT (0.49) | KITHRH3SMN1; SMN2RECQLWNT1 | |
| SCHEMBL30690762 | 0.85 | GSK3B (0.38) | KITHRH3SMN1; SMN2RECQLWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |