Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.50 |
| ▸ | WNT1 | P04628 | 8/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690577 | 0.92 | GSK3B (0.41) | GSK3BDYRK1AWNT1GRM2KIT | |
| SCHEMBL30690725 | 0.92 | GSK3B (0.48) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690544 | 0.90 | GSK3B (0.46) | GSK3BDYRK1AWNT1KITWNT3A | |
| SCHEMBL30690612 | 0.87 | GSK3B (0.47) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690562 | 0.87 | GSK3B (0.45) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690662 | 0.87 | GSK3B (0.45) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690461 | 0.86 | WNT3A (0.42) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690552 | 0.86 | GSK3B (0.38) | GSK3BDYRK1AWNT1GRM2KIT | |
| SCHEMBL30690514 | 0.85 | GSK3B (0.46) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690703 | 0.85 | GSK3B (0.50) | GSK3BDYRK1AWNT1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |