Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 13/20 | 0.44 |
| ▸ | WNT1 | P04628 | 11/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690691 | 0.90 | AURKB (0.37) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690774 | 0.89 | GSK3B (0.41) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690775 | 0.89 | CSF1R (0.37) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690779 | 0.88 | GSK3B (0.35) | GSK3BDYRK1AWNT1HRH3HDAC3 | |
| SCHEMBL30690763 | 0.88 | GSK3B (0.36) | GSK3BDYRK1AWNT1HRH3HDAC3 | |
| SCHEMBL30690658 | 0.88 | CSF1R (0.40) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690656 | 0.88 | GSK3B (0.36) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690663 | 0.87 | GSK3B (0.43) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690769 | 0.87 | GSK3B (0.39) | GSK3BDYRK1AWNT1HRH3CHRM1 | |
| SCHEMBL30690760 | 0.87 | CSF1R (0.40) | GSK3BDYRK1AWNT1HRH3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |