Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.36 |
| ▸ | WNT1 | P04628 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690797 | 0.88 | GSK3B (0.44) | GSK3BDYRK1AWNT1HRH3MCHR1 | |
| SCHEMBL30690765 | 0.87 | HRH3 (0.34) | GSK3BDYRK1AWNT1HRH3MCHR1 | |
| SCHEMBL30690779 | 0.87 | GSK3B (0.35) | GSK3BDYRK1AWNT1HRH3MCHR1 | |
| SCHEMBL30690663 | 0.81 | GSK3B (0.43) | GSK3BDYRK1AWNT1HRH3SMN1; SMN2 | |
| SCHEMBL30690691 | 0.78 | AURKB (0.37) | GSK3BDYRK1AWNT1HRH3KMT2A | |
| SCHEMBL30690774 | 0.76 | GSK3B (0.41) | GSK3BDYRK1AWNT1HRH3SMN1; SMN2 | |
| SCHEMBL30690775 | 0.76 | CSF1R (0.37) | GSK3BDYRK1AWNT1HRH3HDAC3 | |
| SCHEMBL30690658 | 0.75 | CSF1R (0.40) | GSK3BDYRK1AWNT1HRH3HDAC3 | |
| SCHEMBL27275735 | 0.71 | KIT (0.40) | GSK3BDYRK1AWNT1HRH3MCHR1 | |
| SCHEMBL30710731 | 0.70 | HRH3 (0.45) | GSK3BDYRK1AWNT1HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |