Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 11/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690789 | 0.92 | BRAF (0.38) | HDAC1RORCHDAC6EGFRHDAC3 | |
| SCHEMBL30690816 | 0.81 | FGFR3 (0.36) | HDAC1RORCHDAC3NAMPT | |
| SCHEMBL30690811 | 0.77 | DYRK1A (0.38) | HDAC1RORCHDAC3CD274 | |
| SCHEMBL30690642 | 0.74 | CSF1R (0.41) | HDAC1RORCEGFRHDAC3CD274 | |
| SCHEMBL30690639 | 0.74 | GSK3B (0.38) | HDAC1RORCHDAC3 | |
| SCHEMBL30690630 | 0.74 | NPC1 (0.39) | — | |
| SCHEMBL30690647 | 0.72 | DYRK1A (0.41) | RORCNAMPTCD274 | |
| SCHEMBL29448768 | 0.69 | KCNQ3 (0.47) | HDAC1HDAC6NAMPT | |
| SCHEMBL29448781 | 0.69 | NPC1 (0.46) | RORCNAMPT | |
| SCHEMBL20577987 | 0.68 | BRAF (0.47) | RORCNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |