Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 4/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PIR | O00625 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690835 | 0.92 | HDAC1 (0.36) | RORCHDAC1HDAC6EGFRHDAC3 | |
| SCHEMBL30690786 | 0.81 | FGFR1 (0.38) | BRAFRORCKITHDAC1HDAC3 | |
| SCHEMBL30690642 | 0.77 | CSF1R (0.41) | RORCKITCSF1RHDAC1GSK3B | |
| SCHEMBL30690782 | 0.75 | ABL1 (0.32) | HDAC1HDAC3 | |
| SCHEMBL30690811 | 0.75 | DYRK1A (0.38) | RORCKITCSF1RHDAC1GSK3B | |
| SCHEMBL30690630 | 0.74 | NPC1 (0.39) | — | |
| SCHEMBL30690639 | 0.74 | GSK3B (0.38) | RORCKITCSF1RHDAC1GSK3B | |
| SCHEMBL30690647 | 0.73 | DYRK1A (0.41) | RORCKITCSF1RGSK3BNAMPT | |
| SCHEMBL14026831 | 0.72 | BRAF (0.52) | BRAFKITCSF1REGFRNAMPT | |
| SCHEMBL30690763 | 0.71 | GSK3B (0.36) | HDAC1GSK3BHDAC3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |