Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419280 | 0.88 | MAPT (0.50) | MAPTLMNAMEN1TSHRKMT2A | |
| SCHEMBL13419687 | 0.88 | MAPT (0.48) | DPP4DPP9MAPTLMNAMEN1 | |
| SCHEMBL3212037 | 0.84 | DPP4 (0.56) | DPP4MAPTLMNAMEN1KMT2A | |
| SCHEMBL1903391 | 0.80 | GRM5 (0.65) | GRM5DPP4DPP9MAPTLMNA | |
| SCHEMBL15840486 | 0.80 | GRM5 (0.56) | GRM5DPP4DPP9MAPTLMNA | |
| SCHEMBL19002659 | 0.79 | KMT2A (0.61) | GRM5DPP4DPP9MAPTLMNA | |
| SCHEMBL5659051 | 0.78 | HTR1A (0.57) | GRM5MAPTLMNAMEN1TSHR | |
| SCHEMBL3796463 | 0.78 | KMT2A (0.77) | GRM5MAPTLMNAMEN1TSHR | |
| SCHEMBL17208419 | 0.78 | DPP4 (0.55) | GRM5DPP4DPP9MAPTLMNA | |
| SCHEMBL5655876 | 0.77 | NOTUM (0.52) | GRM5MAPTTSHRKMT2AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120443-A | Compounds as adenosine A2a receptor antagonists and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2023-11-24 | — | — | CN | disclosed |